The investigation of indoor air quality has shown that microbial contamination is often a problem in buildings. Recent evidence indicates that fungi are often a part of the picture. A component of the fungal cell wall, 1-3--glucans not only affect human health, they are a marker for the existence of fungi in environmental samples...

This book constitutes the refereed proceedings of the 12th Annual International Conference on Research in Computational Molecular Biology, RECOMB 2008, held in Singapore, in March/April 2008. The 34 revised full papers presented together with the abstracts of 7 keynote talks were carefully reviewed and selected from 193 submissions...

Taking the potential doctor from the thinking process - is this the right career for me? - through to the application, the interview and to university life and beyond. Written by junior doctors who have been through the recent changes in both medical education and the NHS, it explains what life as a medical student and a doctor is really like. Supplemented with many real life personal experiences, it helps readers to gain an unbiased view of their possible future careers.

The second edition of this innovative work again provides a unique perspective on the clinical discovery process by providing input from experts within the NIH on the principles and practice of clinical research. Molecular medicine, genomics, and proteomics have opened vast opportunities for translation of basic science observations to the bedside through clinical research...

This book gives the professional pharmaceutical scientist a basic and comprehensive tool to facilitate the preclinical development process by bringing together, in one resource an overview of the preclinical process along with a compendium of methods and techniques that need to be considered when developing a new drug...

Nutrition plays an important role in optimizing human health and managing disease. Unfortunately, the human response to diet is so incredibly variable that nutritional counseling beyond that of general advice is a complex and challenging task. Nutrigenomics seeks to understand the variability of the individual’s response to food and the underlying mechanisms whereby foods exert their health-promoting activities...

This volume provides a novel insight to the evolutionary and comparative aspects of nitric oxide- nitric oxide synthase system as a central regulator of invertebrate and vertebrate homeostasis. By critically selecting and summarizing the everincreasing number of original studies, these presentations review a variety of important signalling and modulatory roles played by nitric oxide at molecular, cell, organ and organ system levels...

The first edition of this innovative book brought a new perspective to the metabolic and therapeutic aspects of amino acids in clinical nutrition. Since its publication, a number of very important advances have been made in the field and interesting new findings have emerged. Until now, no reference has fully explored the promising new developments and applications in this key area of clinical nutrition...

At the time of the lightbulb's invention, not even the most imaginative thinkers could have predicted the prevention and treatment of disease through genes delivered by electric fields. In Electroporation Protocols: Preclinicaland Clinical Gene Medicine, top researchers provide hands-on protocols describing the process of non-viral delivery of genetic materials such as DNA, oligo-DNA...

General ultrasound in the critically ill describes a new clinical tool: ultrasound for the intensive care and emergency physician. Written by an intensivist familiar with ultrasound, it specifically details findings of immediate clinical relevance throughout its approx...

This book brings together the two disparate worlds of computational text analysis and biology and presents some of the latest methods and applications to proteomics, sequence analysis and gene expression data. Modern genomics generates large and comprehensive data sets but their interpretation requires an understanding of a vast number of genes, their complex functions, and interactions. Keeping up with the literature on a single gene is a challenge itself-for thousands of genes it is simply impossible.
Here, Soumya Raychaudhuri presents the techniques and algorithms needed to access and utilize the vast scientific text, i.e. methods that automatically "read" the literature on all the genes. Including background chapters on the necessary biology, statistics and genomics, in addition to practical examples of interpreting many different types of modern experiments, this book is ideal for students and researchers in computational biology, bioinformatics, genomics, statistics and computer science.

What’s your worst nightmare as a doctor? Missing a life-threatening condition must be among the biggest fears for health professionals. But sometimes the clue to the diagnosis lies in just a single symptom...

This book provides simultaneously a design blueprint, user guide, research agenda, and communication platform for current and future developments in artificial intelligence (AI) approaches to systems biology. It places an emphasis on the molecular dimension of life phenomena and in one chapter on anatomical and functional modeling of the brain.
As design blueprint, the book is intended for scientists and other professionals tasked with developing and using AI technologies in the context of life sciences research. As a user guide, this volume addresses the requirements of researchers to gain a basic understanding of key AI methodologies for life sciences research. Its emphasis is not on an intricate mathematical treatment of the presented AI methodologies. Instead, it aims at providing the users with a clear understanding and practical know-how of the methods. As a research agenda, the book is intended for computer and life science students, teachers, researchers, and managers who want to understand the state of the art of the presented methodologies and the areas in which gaps in our knowledge demand further research and development. Our aim was to maintain the readability and accessibility of a textbook throughout the chapters, rather than compiling a mere reference manual. The book is also intended as a communication platform seeking to bride the cultural and technological gap among key systems biology disciplines. To support this function, contributors have adopted a terminology and approach that appeal to audiences from different backgrounds.

Oregon Health and Science Univ., Portland. Reference, for clinicians and residents, covers the full spectrum of glaucoma problems, including epidemiology and genetics, intraocular pressure, optic nerve, medical therapy, laser therapy, and surgical therapy. Includes pitfalls, references, and illustrations. DNLM: Glaucoma.